小儿重度退化胸腺的不同病理形态表现及其意义

Histopathological difference and their significance on involutional thymus in children

本文对小儿重度退化胸腺64例进行了观察,从组织形态学,可区分为急性、亚急性和慢性,分别为4例(6.2%),17例(26.6%)及43例(67.2%).各类退化的胸腺,除淋巴细胞极度减少为其共同点外,急性者小叶大小、形态基本正常,网状支架暴露;馒性者小叶缩小,支架塌陷;亚急性者介于急慢性之间,而以上皮细胞增生为主要特征.并对各该类的发生、发展过程及其意义,作了探讨.

In this paper, the serious involution of 64 thymuses in children are observed. The results showed that three different stages of morphology of the structure of thymuses were found; the acute involution in 4 cases (6. 3%), subacute in 17 (26. 7%) and chronic in 43 (67. 2%). In addition to the lymphocytes marked decrease as a common point in three groups; in acute cases the shape and size of thymic lobules was normal basically and the reticular supports was exposed. In chronic cases, the lobules became smaller than normal and collapes of the structure; Subacute cases was characterized by epithelial proliferation. So the changes of the thymuses on the pathogenesis, development and thier significance are discussed.