摘要
使用多聚酶链反应(PCR)探讨了单纯疱疹病毒感染与慢性宫颈炎,宫颈癌的关系。结果表明,在31份正常妇女,72份慢性宫颈炎、21份宫颈癌标本中检出HSV阳性分别为4份(13.3%)、25份(34.7%)和12份(57.1%),阳性率呈明显升高的趋势;在慢性宫颈炎患者中,随宫颈糜烂程度的增加,HSV感染率升高。提示HSV感染与慢性宫颈炎、宫颈癌的发生、发展相关;PCR是检测HSV感染灵敏、简便的方法。
Polymerase chain reaction was applied to detect herpes simplex virus infection in cervical samplers .In 31 rormal women, 72 cases with chronic cervicitis, 21 cases with cervical cancer, 4, 25 and 12 ones were HSV-positive respectively, showing remarkably increasing in positive rates.In patients with chronic cervicitis,the infective rate of HSV ran in parallel with the increase in the degree of cervical erosion. The results indicate that HSV infection is associated with the occuration of chronic cervicitis and cervical cancer, and PCR is a sensitive and simple method to detect HSV infection.
出处
《现代妇产科进展》
CSCD
1995年第1期22-24,共3页
Progress in Obstetrics and Gynecology
关键词
单纯疱疹病毒
感杂
聚合酶链反应
子宫颈疾病
Polymerase chain reaction
Herpes simplex virus ( HSV )
Cervical diseases