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肝病患者血清Lp(a)检测的临床意义 被引量:2

Determination of Serum Lipoprotein (a)and Its Clinical Significance in Patientswith Liver Diseases
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摘要 测定急性肝炎、慢性肝炎、肝硬化和重症肝炎患者血清中脂蛋白(a)[PL(a)]的浓度,结果分别为141.3±92.4、72.4±43.2、54.7±37.8和50.9±41.6mg/L,与正常对照组(155.6±99.1mg/L)比较差异显著(P<0.05).其含量随病情加重逐渐降低,与急性肝炎血清GPT呈负相关(r=-0.278,P<0.001).提示血清Lp(a)含量可作为反映肝脏合成功能和损害程度的指标之一。 The serum lipoprotein(a)in the pa-tients with acute hepatitis,chronic hepatitis,cirrho-sis and fulminant hepatitis was determined.The con-centrations were found to be 141.3±92.4mg/L,72.4±43.2mg/L,54.7±37.8mg/L and 50.9±41.6mg/L respectively, There was a significant differencecompared with the control group(155.6±99.1mg/L,P<0.05).The level of serum lipoprotein(a)wasgradually decreased according to the severity of liverdisease and there was a negative correlation with theserum GPT in acute hepatitis (r=-0. 278, P<0.001).The results showed that the level of serumlipoprotein (a)can be one of the markers to evaluatethe synthetic functions and the severity of the dam-age in liver.
作者 张阳根
机构地区 解放军第
出处 《现代诊断与治疗》 CAS 1995年第3期146-147,共2页 Modern Diagnosis and Treatment
关键词 脂蛋白 肝炎 肝硬变 血液生化检测 病理学 Lipoprotein(a)Hepatitis Cir-rhosis
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