一个合成双（多乙酰基－β－D－糖基）硫的简便方法

A CONVENIENT METHOD FOR SYNTHESIS OF BIS (POLY-O-ACETYL β-D-GLYCOPYRANOSYL) SULFIDE

本文报道利用相转移方法由多乙酰基－１－溴代糖合成三个硫代双糖—双（２，３，４，６－四－Ｏ－乙酰基－β－Ｄ吡喃型葡萄糖基）硫（１），（２，３，４，６－四－Ｏ－乙酰基－β－吡南型半乳糖基）硫（２），和双（２，３，４－三－Ｏ－乙酰基－β－Ｄ－吡喃型木糖基）硫（３）的结果。产物１，２与文献中所记载的该化合物物理常数吻合，但产率远高于前人的结果；产物３在文献中未见报道，其结构经元素分析红外、核磁氢谱等给予证实．

In this paper, a phase-transfer catalyzed rnetod for synthesis of three thio-disaccharides-his (2 ,3, 4, 6-tetar-O-acetyl-O-acetyl-β-D-glucopyranosyl sulfide (1 ),bis (2, 3 f 4 , 6-tetra-O-acetyl-β-D-galactopyranosyl) sulfide (2), and his (2, 3, 4, 6-tri-O-acetyl-β-D-xylopyranosyl ) sulfide (3) is described.The precent yields of 1 and 2 are higher than the literature. Compound 3 is a new thio-disaccharide,its structure was confirmed depending upon the elemental analysis and IR,1H-NMR spectra dada.