摘要
本文报告甲氰咪胍预防新生儿急性胃粘膜病变临床疗效观察。118例高危新生儿根据基础疾病随机分成二组。预防组56例，对照组62例。两组胎龄、出生日龄、基础疾病相似。结果预防组AGML的发生率明显低于对照组（P＜0．05）。预防组的平均累积出血量和出血持续时间也明显少于对照组（均P＞0.05）。认为甲氰咪胍用于预防新生儿AGML效果肯定，也未发现明显副作用。
The effect of cimetindine in preventing frorn acute gastric mucos lesion (AGML) of neonates was reported in this paper. There were 118 high risk neonates who were randomly assigned to two groups: 56 cases in prevented groups and 62 cases as control groups. There were on significant difference in the gestational age, the days after birth and underlying diseases between two groups. The results showed that the incidence of AGML in the prevented groups were much lower than those in the control groups (P<0. 05). The mean bleeding amount and the continuation time of bleeding in the prevented groups were also much less than those in the control groups (both P<0. 05). Side effect was not found in the prevented groups during the observation period
出处
《新生儿科杂志》
1995年第1期23-24,共2页
The Journal of Neonatology
