ABO溶血病高胆红素血症的早期监测和防治

EARLY MONITORING AND PREVENTVE TREATMENT FOR CLINICAL APPLICATION IN INFANT'S ABO HDN

本院出生活产新生儿4083例，经直接Coombs’试验（改良法）及／或抗体释放试验阳性诊断为新生儿ABO溶血病152例（占3．7％）其中脐血诊断105例，认为脐血作三项试验能早期诊断本病，当脐血胆红素≥51．3μmol．L（3mg／dL）时可作为发生高胆的预报指标。与常规治疗组比较，早期监测防治组高胆红素血症的发生率及胆红素峰值都明显降低（P＜0．01）；疗程缩短（P＞0．05）。肯定了早期监测防治对预防核黄疸的发生有确切的临床应用价值。

It is presented in this paper that 4083 cases of infants are examined about ABO HDN,which born in the Hospital of Women and Children in Guiyang City. There are 152 cases with ABO HDN in 4083 cases, which is about 3. 7%, including 105 cases that are examined by the serologic test of cord blood. The method of examination is Direct-Coomb's Test Method or Antibody release Method. Form the research, it is given that the serologic test of cord blood can early diagnose ABO HDN. Those infants whose bilirubin levels are over 3mg/dl are diagnosed as hyperbilirubin, which is a forerunner term of ABO HDN. It is sue that the serologic test of cord blood can early diagnose infant's ABO HDN which is proved in clinical applical application by authors.