摘要
目的:观察十六角蒙脱石治疗婴幼儿腹泻病的疗效。方法:单纯婴幼儿腹泻病115例,其中治疗组60例为A组,采用十六角蒙脱石1-2g,po,tid,疗程3d:对照组55例为B组,采用阿米卡星、利巴韦林或双黄连治疗。另外,有其他感染合并腹泻85例,其中治疗组44例为C组,在治疗原发病基础上加服十六角蒙脱石。方法及疗程同A组,对照组41例为D组,在治疗原发病基础上加服庆大霉素、胃酶合剂。结果:A和B2组总有效率依次为97%和69%(P<0.01);C和D2组止泻时间依次为1.8±0.8d和2.5±1.1d(P<0.01)。结论:十六角蒙脱石对单纯性和其他感染合并腹泻均有效,无明显不良反应。
AIM: To observe the effects of dioctahedral smectite(DS) in treating diarrhea of infant. METHODS: One hundred and fifteen patients with single diarrhea were divided into 2 groups. Group A, 60 patients received DS 1-2g,po, tid, for 3 d. Group B, 55 patients were given amikacin, ribavirin or Shuang-huang-lian, moreover, 85 diarrhea patients with other infection who simultaneously received the therapy of origin disease were divided 2 groups also. Group C (44 patients) were given DS. The is same to group A. Group D (41 patients) received gentamicin and pepsin mixture. RESULTS: the total response rates of group A and B are 97%, 69%(P< 0.01), respectively. The period of stopping diarrhea of group C and D are 1. 8±0.8d, 2.5±1.1d(P< 0.01), respectively. CONCLUSION: DS is a effective drug for treating both single diarrhea and diarrhea with other infection diseases and obvious adverse reactions were mild.
出处
《新药与临床》
CSCD
北大核心
1995年第5期277-279,共3页
关键词
十六角蒙脱石
婴儿
腹泻
吸附
粘膜
dioctahedral smectite
infantile diarrhea
adsorption
mucous membrane