地奥心血康胶囊治疗急性心肌梗死

Di-ao-xin-xue-kang capsule in treating acute myocardial infarction

目的：探索地奥心血康（ＤＡＸＸＫ）对急性心肌梗死（ＡＭＩ）的疗效。方法：ＡＭＩ病人８９例，采用随机单盲法分为２组，ＤＡＸＸＫ胶囊组４５例，男性３６例，女性９例，年龄５９±ｓ８ａ．采用ＤＡＸＸＫ２００ｍｇ，ｐｏ，ｔｉｄ，共４ｗｋ。地尔硫组４４例，男性３４例，女性１０例，年龄５８±７ａ．采用盐酸地尔硫３０ｍｇ，ｐｏ，ｔｉｄ，共４ｗｋ。结果：ＤＡＸＸＫ组治疗后心绞痛发作频率须静脉滴注硝酸甘油的量及镇痛药需用次数均显著低于对照组；心功能（ＳＶ，ＣＯ，ＬＶＥＦ，ＳＴＩ）改善亦显著优于对照组；心肌酶（ＧＯＴ，ＣＫ，ＣＫ－ＭＢ，ＬＤＨ）峰值，住院期间心力衰竭及心律失常发生率亦均显著低于对照组。结论：ＤＡＸＸＫ是防治ＡＭＩ有较好疗效的纯中药制剂。

AMI:To observe the effects of Di-ao-xin-xue-kang(DAXXK) capsule in treating acute myocardial infarction (AMI).METHODS:Eighty-nine patients with AMI were randomly assigned to 2 groups with single-blind method.DAXXK group of 45 patients(M 36, F 9; age 59± s 8 a) received DAXXK 200 mg, po,tid, for 4 wk.Diltiazem hydrochloride(Dil) group of 44 patients(M 34,F 10;age 58±7 a) received Dil,30 mg,po,tid,for 4 wk. RESULTS : DAXXK group was better than Dil group in the improvement of clinical symptoms(incidence of anginal attacks.dose of iv nitroglycerin, analgesic times),heart function tests (SV, CO, LVEF, STI). peak value of myocardium enzyme(GOT, CK CK-MB, LDH ) incidences of heart failure and arrhythmia during hospitaliZation. CONCLUSION:DAXXK is better than Dil in preventing and treating AMI.