O-甲基异尿素制备的改进

Improved synthesis of O-methylisoureaYang Shun’an1

报道了供合成药品的中间体Ｏ－甲基异尿素盐的新合成法．在氰氨化钙甲醇溶液中，通入二氧化碳气体，制得氰氨溶液，加无机酸，得到８２．４％～８４．０％收率，９９．１％～９９．８％纯度的Ｏ－甲基异尿素盐．

A new method of preparing O-methylisourea that is as intermediate ofsuppling the synthesis of medicine was reported.The cyanamide was produced by reactingcalcium cyanamide with carbon dioxide in methonol and treating with inorganic acid and theO-methylisourea inorganic salts in high yield(82.4%～84.O%)and purity(99.1%～99.8%)was synthesized.