摘要
分别用抗ＯＭＺ１７６菌（ｄ血清型）和抗ＭＴ６Ｒ菌（ｃ血清型）表面蛋白抗原２２０ＫＤ和１８５ＫＯ分子量的单克隆抗体（ＭｃＡｂ）对血清型变链球菌ｃ、ｄ作用后，通后３Ｈ核素标记测试细菌的粘附性。结果显示：抗２２０ＫＤ、抗１８５ＫＤ表面蛋白抗原的ＭｃＡｂｓ对相应血清型的变链球菌的粘附均呈现明显的抑制作用，两种ＭｃＡｂｓ对不相应血清型变链球茵的粘附也有一定的抑制作用。因而认为ＭｃＡｂ通过局部被动免疫抗粘附原理对变链球菌粘附具有抑制作用。
In this study, we determined the adherence of mutans Streptococci by 3H isotope label method under the use of McAbs against Mutans Streptococci (c,d serotype). The results showed that the adherence of Mutans Streptococci (c,d serotype) was inhibited by McAbs against Mutans Streptococci (c,d serotype).We considered that the effects of McAbs on adherence of Mutans Streptococci was the special rcaction between antigen and antibody in experiment.
出处
《牙体牙髓牙周病学杂志》
CAS
1995年第1期9-10,共2页
Chinese Journal of Conservative Dentistry
关键词
单克隆抗体
变链球菌
粘附
龋齿
预防
Monoclonal antibody, Mutans Streptococci, Adherence.
