丹参化学成分的研究概况

Review on the Chemical Constituents of the Roots of Salvia miltiorrhiza

丹参是中医传统使用的安神止痛,活血化瘀药。近年来因发现其对冠心病,心绞痛,心肌梗塞有疗效而广泛应用于临床。本文对丹参脂溶性和水溶性成分的提取分离、结构测定、光谱特征、合成,特别是70年代以来丹参煎剂、注射液以及有效成分对于治疗心血管系统疾病的药理作用和临床应用研究概况作一综述和展望。

Danshen(Salvia miltiorrhiza Bunge)is a traditional medicine in China used for the treatment of blooddifficulties,hemorrhages and viral hepatitis.Recently,it is used for the treatment of coronary heart diseaseas a clinically important drug.The present paper outlines the research on isolation,structure determination andsynthesis of major components of Dansben,in addition to its pharmacological study and clinical application forcoronary heart disease since 1970.