摘要
作者测定了187例颅脑损伤病人入院时(≤24小时)血糖含量。结果:所有病人平均血糖水平都明显高于正常值(P<0.05)。入院时按GCS(Glasgow昏迷评分)3~8分、9~11分、12~15分分三组,其血糖含量分别为9.46±1.22、7.77±0.89和6.09±0.43(mmol/L),说明血糖水平与GCS显露相关(P<0.001)。伤后二月内恢复良好、差、死亡三组病人入院时血糖分别为6.16±0.34、9.03±1.60和10.77±1.65(mmol/L),入院时血糖≥11.10mmol/L者死亡率明显增高(P<0.001),提示入院时血糖水平与 GOS(Glasgow预后评分)亦有显著相关(P<0.001)。本文结合文献讨论了颅脑损伤后血糖升高的机理与伤情及预后的关系。
On admission, Serum glucose level was measured in 187 Patients with craniocerebralinjury within 24 hours after injury.All of these patients Serum glucose level were Signifi-cantly higher than that of normal (P < 0.05). The mean serum glucose level of patientswith GCS of 3 - 8, 9 - 11, 12 - 15 was 9.46±1.22, 7.77±0.89 an 6.09±0.43(mmol/L) respectively. The low the GCS score was, the higher the serum glucose levelwas (P < 0.001). The patients in the 3 groups of the dead, poor recovery and good re-covery in two months after injury had mean serum glucose levels of 10.77±1.65, 9.03±1.65 and 6.16±0. 34 (mmol/L) respectively. So it showed that the serum glucose levelwas also correlated with GOS of these patients (P < 0. 001). The patients with serum glu-cose level≥11. 1mmol/L had significantly higher mortality (P < 0.001). This result sug-gests tha Serum glucose determination on admission may be helpful to evaluate the severityand prognosis of patients with brain injury.