摘要
应用自制的DMF为标准品,建立一种测定糖化血清蛋白(GSP)的新方法——血清果糖胺(SFA)测定法。应用此方法对37名健康人和52例糖尿病人进行SFA测定,二者间差别显著。糖尿病患者的SFA与空腹血糖(FBG)及糖化血红蛋白(HbA_1)显著相关,与测定前3周的FBG均值相关性最好,17例无微血管并发症的糖尿病患者和15例有微血管并发症的糖尿病患者SFA之间无显著差异。本文提示SFA可以反映糖尿病患者的高血糖状态,对了解近期血糖控制情况有实用价值。
A simple colorimetric assay for glycated serum protein-serum fructosamine assay was developed using the standard 1-deoxy, 1-morpholinofructose (DMF) prepared in our laboratory. Normal and diabetic populations can be discriminated well. In the diabetic group, value for SFA correlated with those for fasting blood glucose (FBG) and glycated hemoglobin (HbAI). Thus SFA may be regarded as a precise objective.
出处
《中国医科大学学报》
CAS
CSCD
1989年第4期305-308,共4页
Journal of China Medical University
