FCA-iRNA对正常小鼠胸腺.脾形态结构及细胞免疫的影响

THE EFFECTS OF FCA-iRNA ON THE MORFHOLCGY OF THYMUS AND SPLEEN AND ON CELLULAR IMMUNITY IN NORMAL MICE

本文探讨了福氏完全佐剂免疫核糖核酸对正常小鼠胸腺、脾形态结构的影响。观察结果:胸腺重量增加,皮质增厚,胸腺细胞密集,母细胞型胸腺细胞和核分裂增多;脾重量增加,脾小体数目增多,体积增大;同时使末梢血白细胞、淋巴细胞,尤其T淋巴细胞升高。

The effects of FCA-iRNA on the morphology of thymus and spleen in normal mice were explored. It was found that FCA-iRNA could augment thymus weight, thicken thymus cortex, intonsify thymocytes and increase the number of lymphoblast and mitosis; FCA-iRNA could also increaee the spleen weight and number of the spleen corpus; and it could raise the number of leukocyte and lymphocytes, especially T lymphocytes in peripheral blood.