重症病毒性肝炎的病原学分型的探讨

STUDY ON ETIOLOGIC CLASSIFICATION OF FULMINANT VIRAL HEPATITIS

本文对53例经临床与肝活检病理诊断为重症病毒性肝炎病例,采用美国Abbott试剂盒检测甲肝IgM抗体,乙肝表面抗原、抗体,e抗原、抗体,核心抗体及其IgM抗体;同时用英国“NOCTCH”试剂盒检测Delta抗原、总抗体及IgM抗体。发现甲肝病毒感染2例(4%);乙肝病毒感染最多,27例(51%);丙肝病毒次之,21例(39%);丁型肝炎病毒1例(2%);甲、乙型肝炎病毒重叠感染及CMV病毒所致各1例。

The specimens of 53 fulminant viral hepatitis, diagnosed by clinical data and biopsy, were tested by Abbott kits for HBsAg, anti-HBs, e-Ag, anti-e, anti-HBc, anti-HBc-IgM, and by NOCTCH kits for anti-delta, anti-delta-IgM and deltassay Ag. The results were as follows: 2 cases of them were caused by the hepatitis A virus. 27 of them were caused by the hepatitis B virus. 21 of them were caused by the N-A N-B hepatitis virus. One case was caused by the hepatitis D (delta) virus, type A and B hepatitis viral super-infection, and CMV, respectively. The prognosis of this disease is discussed herein.