摘要
对药物动力学,特别是透膜转运和代谢过程作了综述。以吗啡类镇痛药和磺胺药为例说明了定量构动关系研究在药物设计过程中的应用。
Pharmacokinetics, especially permeability to membranes and
metabolism, is reviewed. The application of quantitative structure-pharmacokine-
tics relationship (QSPR) in the drug design is introduced, using morphine an-
algesics and sulfa-drugs as examples.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1989年第5期230-236,共7页
Chinese Journal of Pharmaceuticals
关键词
药代动力学
定量构动关系
药物设计
pharmacokinetics, permeability to membrane, metabolism, QSPR,drug design, morphines analgesics, sulfamide
