防风及其地区习用品解热镇痛作用的比较研究

Comparative Studies on the Febrifugal and Analgesic Activities Of Chinese Drug Fang-feng,Root of Saposhnikovia Divaricata(Turcz.) Schischk, and Its Substitutes

本文通过对防风与主要地区习用品的解热镇痛作用及毒性比较,发现防风有明显的解热与镇痛作用,母防风镇痛作用约为防风的70—85%,而解热作用只及防风的55%左右,但毒性较小。松叶防风与竹叶防风的解热镇痛作用与防风相似而毒性较低。河南水防风与川防风的解热镇痛作用介于防风与母防风之间,但毒性较强。青海小防风的解热镇痛效果均差。

The Chinese drug Fang-feng derived from Saposhnikovia divaricata (Turcz.) Schischk is the root of the unflowering plant, while that of the flowering plant is usually called the 'Female Fang-feng' . This paper reports an experimental study on the toxicity, febrifugal and analgesic activities of Fang-feng, the Female Fang-feng and five kinds of substitutes used in certain districts of China. The results showed that Fang-feng has significant analgesic and febrifugal activities. The Female Fang-feng has 70-85% of the analgesic activity and about 55% of the febrifugal activity of Fang-feng, but also has a lower toxicity. The root of Seseli mairei Wolff and S. yunnanensis Franch. has activities similar to those of Fang-feng. The root of Libanotis laticalycina Shan et Shah and Peucedanum dielsianum Fedde et Wolff is less effective and more toxic. The root of Carum carvi L shows practically no febrifugal and analgesic effects.