感染性休克热厥气脱证的研究

Reseorch on Syndrome of Cold Limbs due to Excess of Heat in Infected Shock

本文首次提出了感染性休克常见的一个临床证型——热厥气脱证。对该证的概念、立论依据、病因病机、诊查和治疗要点做了系统论述。并针对其因整体气机、脏腑气机、细胞气机郁闭导致全身性气滞络瘀和宗气外脱的病机,以行气活血、扶正固脱为大法,研制了新的辨证针剂——抗厥注射液。临床和药理实验结果表明,抗厥注射液主要是通过升压、强心、增加重要脏器的血液灌注.抑制血栓素和脂质过氧化物的生成等环节,调整了整体气机、脏腑气机和细胞气机,从而发挥了抗厥固脱作用。

A commone clinical pattern in infected shock——cold limbs due to excess of heat——summed up for the first time by the author who systematically discusses the concept of the syndrome, basis for setting forth his views, pathology, diagnosis and the principles of treatment. Proceeding from the pathology of Qi stagnation and collateral stasis in the whole body caused by pent-up Qi in cells, viscera and the whol(?) body, a new injection, the anti-shock injection, has been developed in accordance with the main principles of promoting the flow of Qi and blood circulation and strengthening the body resistance to prevent the syndrome. The results of clinical and pharmacological experiments show that the injection acts through a number of aspects, (?)uch as raising the blood pressure, promoting the heart function increasing the perfusion of blood and inhibiting the production of thromboxane and lipidic peroxide, (Original article on page 7).