1,4-二硝基-2,3-二硝胺基哌嗪的合成

Synthesis of 1,4-Dinitro-2,3-dinitraminepiperazine

本文以乙二胺、乙二醛和脲为原料,通过Mannich反应,合成出2,5,7,9-四氮杂双环[4.3.0]壬-8-酮盐酸盐(1);化合物1亚硝化给出2,5-二亚硝基-2,5,7,9-四氮杂双环[4.3.0]壬-8-酮(2);硝化化合物2制得2,5,7,9-四硝基-2,5,7,9-四氮杂双环[4.3.0]壬-8-酮(3);化合物3水解制得1,4-二硝基-2,3-二硝胺基哌嗪(4)。

The synthesis of 2, 5, 7, 9-tetrazabicyclo [4. 3. 0] nonan-8-one hydrochloride (1) from ethylenediamine, glyoxal and urea by Mannich reaction was reported. Nitrosation of compound 1 gave 2,5-dinitroso-2, 5, 7, 9-tetrazabicyclo [ 4. 3. 0] nonan-8-one (2). Nitration of compound 2 gave 2, 5, 7, 9-tetranitro-2, 5, 7, 9-tetrazabicyclo [4. 3. 0] nonan-8-one (3). 1,4-Dinitro-2, 3-dinitraminepiperazine (4) was synthetized by hydrolysis of compound 3.