5-芳酰氨基-2-苯基-2H-1,2,4-噻二唑-3-酮的合成

Synthesis of 5-Aroylamino-2-Phenyl-2H-1,2,4-Thiadiazol-3-one

用1-芳酰基-5-苯基-2-硫代双脲与溴进行氧化成环反应制备了九个新的5-芳酰氨基-2-苯基-2H-1,2,4-噻二唑-3-酮,相应的1-芳酰基-5-苯基-2-硫代双脲可以通过苯基脲与酰基异硫氰酸酯加成制得。

Nine new 5-aroylamino-2-phenyl-2H-1.2,4-thiadiazol-3-ones were prepared from the corresponding 1-aroyl-5-phenyl-2-thiobiurets. which were generated through the addition of phenylaurea to the corresponding aroyl isothiocyanates by the oxidative cyclolization with bromine.