电针对大鼠下丘脑背内侧核痛敏神经元放电的影响

Effect of Electroacupuncture on the Discharges of Pain-sensitive Neurons in the Hypothalamic Dorsomedial Nucleus of Rats

用玻璃微电极记录SD大鼠下丘脑背内侧核（DMH）病敏神经元的放电。电针“足三里”和“三阴交”后观察到：（1）DMH痛兴奋单位的自发放电和痛诱发放电的频率明显减少。且痛诱发放电的时程明显缩短；（2）DMH痛抑制单位的自发放电频率增加，并解除伤害性刺激引起的抑制效应。上述结果提示：DMH参与针刺镇痛。

The discharges of pain-sensitlve neurons of the hypothalamic dorsomedial nucleus (DMH) in Sprague-Dawley rats were recorded with glass microelectrodes, After electroacupuncture acupoints' Zusanli'and 'Sanyinjiao', the rate of spontaneous discharges and the rate and duration of the pain-evoked discharges of pain-excitatory units of DMH were pro foundly decreased,and the spontaneous firing rate of pain-inhibitory units was increased while their inhibitory response to nociceptive stimulation was released by the electroacupuncture.The results mentioned above suggest that DMH participates in the activity of acupuncture analgesia