电刺激红核对针刺镇痛效应的影响

Effect of Electrical Stimulation of Red Nucleus on Acupuncture Analgesia

通常认为红核（RN）的主要生理机能是调节躯体运动。本实验旨在探讨RN兴奋对针刺效应及痛觉传入信息的影响。电刺激RN和电针“足三里”穴均可抑制脊髓背角神经元的C反应，电刺激RN加强电针的镇痛效应，纳络酮翻转电刺激RN而产生的对C反应的抑制效应。结果表明：RN除调节躯体运动外，对感觉传入也有调制作用，且这种对感觉的调制作用有内阿片系统的参与。

The function of red nucleus (RN) was important in motor control. This work was to study whether the RN influenced the effect of EA and the somatosensory afferent system. C-responses of spinal dorsal horn neurons(SDHN) were recorded as nociceptive responses- Electrical stimulation of RN could intensify the inhibitory effect of EA and inhibit nociptive reponse of SDHN. Naloxone(NX) could completely block that inhibition of RN- The result inferred that the RN can modulate both of somatomotion and somatosense. The endogenous opiate system is involved in the somatosensory modulation of RN