新生儿呼吸衰竭血浆心钠素的临床意义

Clinical Application of SANP on Newborn's Respiratary Failure

本文采用放射免疫学方法测定５８例围产窒息新生儿血浆心钠素（ＳＡＮＰ）的变化。结果表现，随窒息加重ＳＡＮＰ水平增高。窒息组（５２４．１±１３６．８ｎｇ／Ｌ），重度窒息并呼衰组（７２１．１±１５８．７ｎｇ／Ｌ）与对照组（２１２．１±６９．２ｎｇ／Ｌ）比较均有非常显著意义，Ｐ＜０．０１）。随窒息好转逐渐恢复（２３４．６±５８．６ｎｇ／Ｌ），故血浆中的ＳＡＮＰ变化可做为窒息复苏、判断心脏功能指标之一。

We determined the variation of SANP in 58 perinatal suffocated newborns by radioimmunoassay.It shows that the inereasing of the SANP is in proportion to the seriousness of suffocation. SANP level of suffocated group( 524. 1± 136. 8mg/L) is significantly higher as compared with the groups of severe suffocation complicated with respiratary failure (721 . 2± 1 58. 7ng/L) and the control(212. 1±169. 2ng/L) ,and the level of SANP returned normal, with improvement Variation of SANP may be one of criteria to identify heart'or lung function, as well as the recovery of suffocation.