大肠绒毛肿瘤17例临床报告

Villous Tumor.A Report of 17 Cases

本文报道我院1963年至1986年临床治疗大肠绒毛肿瘤17例。除1例位于盲肠外,其余位于直肠,直肠乙状结肠及乙状结肠。多数病人发病在40～70岁之间。性别差异不著。常见症状为便血、粘液便及腹隐痛。术前活检与术后组织学检查对照,其误诊率为47.3％。肿瘤恶变率高达76.3％,必须将肿瘤完整切除,进行组织学全面检查方可获得正确诊断;一旦发现肿瘤已发展为浸润癌,应行根治性手术。

During 1963-1986 17 cases of villous tumor of the large intestine were seen. All patients had their tumor located in the rectum, recto-sigmoid or sigmoid colon ex- cept one in the cecum. A majority of the patients were in their fourth-seventh decade of life. Most common symptoms were rectal bleeding, diarrhea with mucoid stools or abdominal pain. Carcinomatous lesions in the villous tumor were missed on biopsy in 47.3 %of this group. Hence, complete excision of these tumors for an accurate histo- logic diagnosis is mandatory. Because of the high incidence of associated carcinoma, 76.3% in this series, an excision of entire lesion or segmental resection of the invol- ved colon is preferrable. In the event of occurrence of invasive carcinoma, it should be treated radically.