消化道恶性肿瘤出血与病理关系

Histopathology of Digestive Tract Cancer and the Bleeding Tendency

我们从1984年11月至1986年5月研究150例消化道恶性肿瘤病理标本,病理诊断根据WHO分类方法。出血程度根据临床与病理检查。150例中,138例(85.5％)有出血,22例(14.5％)无出血。直肠癌出血发生率明显高于其它部位;粘液腺癌出血发生率低;高分化与中分化腺癌出血发生率比低分化癌要高;溃疡型出血发生率比菜花型与管腔浸润型高;出血与肿瘤大小,侵犯及转移程度无关。

From November 1984 to May 1986, 150 inpatients with malignant tumors of diges- tiye tract as related to bleeding were studied. The histologic classification was ac- cording to the criteria of WHO. The degree of hemorrhage was evaluated on the basis of clinical findings and pathologic studies. Hemorrhagic evidences were noted in 138 of the 150 cases (85.5％). Carcinomas of the rectum showed greater tendency of bleeding than did lesions of stomach, small intestine and colon. Mucinous adeno- carcinomas tended to have less severe degree of hemorrhage than did nonmucinous adenocarcinomas. Well and moderately differentiated carcinomas had marked hemor- rhage than did poorly differentiated carcinomas. Ulcerative carcinomas had marked henorrhage than did cauliflower or infiltrative type. The size of lesion and the ex- tent of spread of tumors did not correlate with hemorrhage.