慢性萎缩性胃炎118例胃镜随访

Follow-up Observation of Chronic Atrophic Gastritis

我院对118例慢性萎缩性胃炎(CAG)的纤维内窥镜结果进行随访,其中超过41岁以上77例占65.3％,在3-9年内胃镜检查超过3次以上者38例占32.2％,最多可达5次。并对这些患者进行了综合治疗。结果4例胃粘膜炎症消失,19例CAG转为表浅性胃炎,显效率为19.5％。5例CAG因重度肠化及/或不典型增生,而疑早癌而行手术治疗占4.28％,病理结果仍为CAG,4例术后症状消失。6例CAG发生恶变,经手术病理证实恶变率为5.08％、讨论了癌变与肠化、不典型增生的关系。强调CAG胃镜定期随访的重要性。

Between 1976 and 1987 118 patients (65.25% were 41 years of age or older) with chronic atrophic gastritis (CAG) were followed up by gastroscopy; 32.2% were examined atleast three times during the 3-9 years follow-up period. All the patients in this series were subjected to medicinal treatment. During the follow-up period, 4 recovered completely, 19 transformed into superficial gastritis, 5 who had beavy degree intestinal metaplasia and/or dysplasia were operated on,6 devel- oped gastric carcinoma. The role of campylbacteria pyloridis and bile reflux in CAG was discussed.