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血清醛缩酶同功酶 A 测定对肝癌及消化系其它恶性肿瘤的诊断研究 被引量:2

Diagnostic Value of Serum Aldolase A Determination in Patients with Hepatoma and Other Digestive Tract Malignancies
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摘要 本文应用放射免疫沉淀法对94例经病理证实的消化系统恶性肿瘤(包括食管癌30例、胃癌47例、结肠直肠癌5例、原发性肝癌7例、胰腺癌2例、胆囊癌3例)作Ald-A测定。另有31例健康者作对照组,正常人血清Ald-A在0~18U/dl之间,均值为9.26±5.0U/dl(X±SD)。食管癌、胃癌、结肠直肠癌、胰腺癌和胆囊癌的Ald-A均值分别为10.23±9.1U/dl、9.94±9.2U/dl、12±8.21U/dl、9.5U/dl和4.83±2.84U/dl。与正常对照组比较无明显差异(P>0.05)。但原发性肝癌患者的血清Ald-A值明显增高,均值为30.03±23.54U/dl(P<0.001)。本文研究结果提示,用放免法测定Ald-A有助于肝癌病人的诊断。 Serum aldolase A level was measured by immunoprecipitative assay in 94 patients with various digestive malignancies (esophagus 30, stomach 47, colon 5, liver 7, pancreas 2, gall-bladder 3) and in 31 healthy individuals as control. The results show- ed that there was no significant difference (P>0.05) between studied patients and normal individuals except in patients with hepatoma. The mean value of ALD-A in hepatoma patients was 30.03±23.54 u/dl, much higher than other subjects inves- tigated.
出处 《中国肿瘤临床》 CAS CSCD 北大核心 1989年第4期195-197,共3页 Chinese Journal of Clinical Oncology
关键词 肝癌 消化系肿瘤 醛缩酶 Serum aldolase A Liver carcinoma Digestive system Immunoprecipitative assay
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  • 1陈新刚,舒建德,谢弘,刘德腾,孙培南.人醛缩酶A单克隆抗体的制备及应用[J].中国免疫学杂志,1995,11(2):88-91. 被引量:3
  • 2陈江华,王毓三.3-磷酸甘油脱氢酶偶联法测定血清醛缩酶活性[J].临床检验杂志,1996,14(6):287-290. 被引量:5
  • 3赵建华,王毓三.醛缩酶同工酶琼脂糖电泳测定法[J].临床检验杂志,1997,15(1):9-12. 被引量:4
  • 4殷正丰,吴孟超.异常凝血酶原测定对原发性肝癌的诊断价值[J]第二军医大学学报,1988(03).
  • 5张宝初,黄兴耀,王墨荣.血清硷性磷酸酶和γ-谷氨酰转酞酶联合检测对原发性肝癌的临床价值[J]中国肿瘤临床,1988(06).
  • 6梁小浣,余竹元,汤钊猷.脂结合唾液酸测定在原发性肝癌临床应用中的价值[J]肿瘤,1986(04).
  • 7上海医学1985年(第8卷)总目录[J]上海医学,1985(12).
  • 8李航,黎乐群.细针肝穿活检对原发性肝癌的诊断价值及针道种植的预防[J].中华肝脏病杂志.2000(05)
  • 9Khaleque Newaz Khan,Keisuke Nakata,Kazuhiko Nakao,Yuji Kato,Katsumi Eguchi.Use of FDP and F1P Aldolase to Detect Tumorous and Nontumorous Tissue Damage by Ethanol Injection of Hepatocellular Carcinoma[J].Digestive Diseases and Sciences.1999(8)
  • 10Khan KN,Tsutsumi T,Nakata K,et al.Sodium butyrate induces alkaline phosphatase gene expression in human hepatoma cells[].Journal of Gastroenterology.1999

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