南京周围地区非何杰金氏淋巴瘤危险因素初探

Risk Factors of Non-Hodgkin's Lymphomas(NHL)in the Area Surrounding Nanjing.A Preliminary Report

1985年1月至1986年6月,我们对南京周围地区的93例非何杰金氏淋巴瘤(NHL)进行了病例对照研究。所有病例均从当地医院选择并经病理确诊。病例和对照按年龄、性别及民族配对,对各种因素计算了X^2值,暴露比数比和95％可信限。结果发现,NHL与职业、经济状况和饮水类型有重要的联系;与其它人相比,农民患NHL的危险性要高4倍;经济状况越差,患NHL危险性越大;饮河水或井水者患NHL危险性要比饮自来水者高5倍;而常吃胡萝卜则有保护作用。

A case-control study of risk factors of NHL on 93 matched pairs was carried out in the area surrounding Nanjing between January 1985 and June 1986. The cases selec- ted from local hospitals were all histologically confirmed. Cases and controls were macthed with respect to sex, age and race. The exposure odds ratio (EOR) of various factors and their 95% confidence limits and X^2 were calculated. It was found that NHL is significantly related to profession, economic condition and the source of drink- ing water. The risk of suffering from NHL in farmer is more than fourfold higher than in other persons. The lower is the economic condition, the greater is the GOR. Compared to tap water drinking people, the risk increased to more than fivefold for persons who drink river water or well water. Carrot plays an important role in the prevention of NHL.