涎腺癌196例临床分析

Carcinoma of Salivary Glands.A Clinical Analysis of 196 Cases

自1975年至1985年间,我院收治涎腺癌共196例,占同期头颈部恶性肿瘤的4.2％。男115例,女81例,年龄6.5-78岁。腮腺93例,颌下腺24例,舌下腺1例,小涎腺78例。本组随访满3、5、10年以上各占153例、121例和39例。3、5、10年生存率分别为75.8％、66.1％、59％。病变位于大涎腺与小涎腺生存率相近。Ⅰ-Ⅳ期5年生存率分别为88.5％、70.7％、52.6％和45.0％。术后放射治疗能改善晚期癌(Ⅲ、Ⅳ期)的生存率。本组术后局部复发率为35.5％,远处转移率为7.1％。

In 1975-1985, 196 patients with carcinoma of salivary glands were operated upon. These patients constituted 4.296 of all head and neck carcinomas treated during the same period of time. There were 115 males and 81 females. Age of the patients ranged from 6.5 to 78 years. The parotid glands were involved in 93 instances, submaxillary glands in 24, sublingual glands in 1 and minor salivary glands in 78. One hundred and fifty three patients were followed up for 3 years, 121 for 5 years and 39 for 10 years. The 3-, 5- and 10-year survival rates were 75.8%, 66.1% and 59% respectively. The 5-year survival rates for stage Ⅰ-Ⅳ were 88.5%, 70.7%, 52.6% and 45.0% respectiyely. In advanced cases (stage Ⅲ, Ⅳ) the survial could be improved by postoperative radiotherapy. The overall recurrence rate in this series was 35.5% and the distant metastasis rate 7.1%.