B超引导下瘤内注射无水酒精治疗肝癌

Intratumoral Injection of Absolute Alcohol under the Guidance of B-mode Ultrasonography in the Treatment of Huge Nodular Hepatoma

本文报道采用酒精瘤内注射治疗经病理证实的14例中晚期肝癌患者。经随访3～15个月,其中1例肝内病灶明显缩小(由12×12cm～2.1×2.0cm),随访超过15个月仍健在。2例治疗中瘤体缩小一半,但1个月后又增大。4例治疗后,AFP下降一半。其余7例无效。瘤内注射,尽管是一姑息性疗法,但在B超引导下既能显示瘤体与相邻组织的关系,又能看到进针的运动过程,针尖位置及酒精在瘤内弥散呈现强光团的动态情景。它与肝动脉的各种栓塞疗法相比,作者认为本方法简便、安全、准确及并发症少,是值得推广的新疗法。

Under the guidance of B-mode ultrasonography 14 cases of advanced hepatoma were treated by intratumoral injection of absolute alcohol and followed up for peri- ods of 3-15 months. One case is still living 15 months after treatment, with the tu- mor dimension reduced from 12×12cm to 2.1 ×2.0cm. In 2 cases the lesions were noticed to reduce in size while undergoing treatment, but enlarged again in one month af- ter completion of the therapy. Four cases had their serum AFP declined while the other 7 cases showed no response. In contrast to various types of hepatic artery em- bolization this method has the advantages of being simple, quick, safe, accurate and less complication and warrants recommendation as palliative measure for advanced hepatoma of nodular type.