摘要
鳖制剂可提高小鼠血浆蛋白质水平，使白蛋白由2．67±0．44升到3．25±0．34g／dl，总蛋白由5．34±0．88上升到6．74±1．38g／dl；同时鳖制剂也可加快肝，脾DNA和蛋白质合成的速度，使肝DNA，蛋白质的放射性比活度分别由2．42±0．71上升到3．90±1．41和由12．81±5．83上升到21．69±4．84dpm／μg，脾DNA，蛋白质的放射性比活度分别从19．04±10．54上升到41．88±18．47和由16．34±7．01上升到23．12±4．38dpm／μg，鳖制剂对骨髓细胞的DNA合成和小鼠血红蛋白水平无明显作用，本文结果为鳖制剂作用机制的研究提供了有价值的资料。
Extract Amyda sinensis raised the levels of Plasma proteins. Plasma albumin was raised from 2.67±0.44 to 3.25±0.34g/dl and the total Plasma protein from 5.34±0.88 to 6. 74 ±1. 38 /dl. 3H-TdR and .3H-Leucine incorporation techniques were used to measure the syntheses rate of DAN and protein .The rates was accelerated.The specifie activities of DNA and protein of liver got up to 3.90±1.41 from 2.42±0.71 dpm/μg, and 21.69±4.84 from 12.81 ±5.83 dpm/μg, respectively.Those of spleen got up to 41.88±18.47 from 19.04±10.54 dpm/μg and 23.12±4.38 from 16.34±7.01 d pm/μg, respectively. Extract Amyda sinensis had no effect on DNA synthesis of bone marrow cells and did not raise the hemoglobin level in mice. The results suggest that Extract Amyda sinensis has bioactive substance that accelcrate synthcses of DNA and protein.
出处
《中草药》
CAS
CSCD
北大核心
1995年第3期138-140,共3页
Chinese Traditional and Herbal Drugs
