超声显像筛查高危新生儿脑损伤的研究

Study on Sieving Brain Injury of High Risk Neonates by Ultrasonic Visualization

总结了利用头颅B超对500例高危新生儿脑损伤的筛查,并配合头颅CT进行了对照研究。结果检出脑损伤150例,发生率30％,其中缺氧缺血性脑病135例(27％),颅内出血15例(3％),并与正常组(无任何高危因素)做了对照,P<0.001,有非常显著性差异;经头颅B超证实脑损伤患儿75例又经头颅CT检查,其中2例不符合,符合率97％;被检出脑损伤有症状者83例(55％),无症状者67例(45％)。对部分无症状脑损伤患儿分别在生后3、7、15天进行了新生儿行为评分测定,并与对照组进行了比较P<0.001,有非常显著性差异,说明通过大面积筛查大大提高了诊断率。本文同时探讨了发病的高危因素,从而提出了预防措施。

150 brain injury patients of 500 high risk neonates have been sieved out by skall B ultrasono-graphy. 135 of them are anoxemic encephalopathy. 15 of them are intracranial hemorrhage. There are very significant difference from normal group(P<0.001). 75 of 150 brain injury patients sieved out in skall B ultrasonography have been also examinated in skall CT. The results showed that the coincidence rate of examination in B ultrasonography and in CT is 97%. The new -born action of some noendeictic brain injury patients have been evaluated in 3. 7 and 15 days after birth. There are very significant difference from normal groupC P<0.001).