摘要
对35~59岁农民4332人进行脑卒中发病率的10年随访.随访率97.17%,10年发生脑卒中86例.年标化发病率1.94‰;.男性标化率2.40‰。,女性1.90‰。发现基线收缩压、舒张压水平与脑卒中发病呈正相关。男性大量吸烟组发病率(5.37%),较不吸烟组(1.90%)高,RR2.83;男性大量饮酒组发病率5.59%,不饮酒为1.72%,RR3.25;高血压大量饮酒组脑卒中发生率46.47%.较正常血压不饮酒组(0.74%)显著高,RR63.07。血清胆固醇的均值女性高于男性(P<0.01)。女性基线血压水平及高血压患病率明显高于男性,但脑卒中发病率及低于男性,分析其原因.女性有多于男性的有利因素,即血TC高,少量吸烟,不饮或少量饮酒。
A cohort of 4332 farmers aged 35~ 59 was followed-up for 10 years and its stroke incidence was studied. Thefollow - up rate was 97. 17%, 86 cases of stroke occurred inthis period. An annual standardized incidence was 1. 94/1000(2. 40/1000 in male, 1. 90/1000 in female). Risk factor analysisshowed that, (1 ) the mean systolic and diastolic blood pressurelevel in the baseline survey was positively correlated to thestroke incidence. (2 )the stroke incidence in heavy men smokerswas 5. 37%, in heavy men drinkers was 5. 59 % and in heavydrinkers with hypertension was 46. 67 %. (3 ) the mean serumtotal cholesterol (TC) in women was higher than that in men(P< 0. 01 ). It seems that the higher TC. lower drinking andsmoking rates might be protective factors against stroke inwomen group,though they had higher blood pressure and hyPertension prevalence rate than that in men group.
基金
国家"八五"科技攻关课题!85-915-01-01
关键词
中风
发病率
影响因素
stroke
incidence
drinking
smoking
serum total cholesterol
hypertension