摘要
通过观察易卒中型肾血管性高血压大鼠心脏的病理形态．发现所有高血压大鼠均有不同程度的左心室肥厚和心肌内小冠状动脉病变，但大冠状动脉无粥样硬化，在此基础上自发性心肌梗塞率为41．8％。表明心室肥厚和心肌内小冠状动脉病变在高血压所致的心肌缺血性损害中起重要作用。
Cardiac lesions were observed morphologically in 55 stroke-prone renovascular hypertensive rats (RHRsp ). Left ventricular hypertrophy and small coronary arterial lesions in myocardium were discovered in all the RHRsp, with is no atherosclerosis in large coronary arteries. On the basis of left ventricular hypertrophy,myocardial infarction occurred spontaneously in 41. 8% of RHRsp. These results suggest cardiac hypertrophy may play important roles in the ischemic cardiac lesions of hypertensive subjects.
关键词
肾性高血压
易卒中型
心脏损害
renovascular hypertension
rats
myocardial infarction
