摘要
比较在轻度至中度高血压中用氨氯地平及硝苯地平治疗4周的疗效与安全性，结果显示氨氯地平降压作用缓慢而持久，早期血管性不良反应较少。无停药后高血压性反跳效应，不影响神经内分泌系统。
Responsive rate and safety of amlodipine andnifedipine were compared in patients with mild or moderate essential hypertension. The results showed that the antihypertensive actions of amlodipine were slow and long lasting. Itsadverse effects related to vasodilation were fewer than those ofnifedipine. No hypertension rebound effects was found whendrug is suddenly stopped and no neuroendocrine adverse effectwas found. It is suggested that amlodipine is not only a safe.effective,but also a promising antihypertensive agent.
