摘要
对广州市1989年仅有的两家加工纯棉工厂1320名工人作研究,发现可吸入性棉尘与总尘浓度、内毒素含量中位数分别为0.71(0.41~1.51)与5.28(3.04~12.32)mg/m3,2007(1236~4100)Eu/m3;呼吸系统异常的检出率、慢性气管炎及棉尘病患病率分别为:(1)典型星期一症状9.0%,(2)班后FEV1下降≥5%为16.8%,(3)班后FEV1下降≥10%为4.2%,(4)班前FEV1小于预计值80%为6.1%,(5)FEV1/FVC<75%为4.0%,(6)咳嗽和(或)咳痰18.2%,(7)慢性气管炎10.9%,(8)棉尘病〔(1)+(2)〕患病率为1.7%。与对照组比较,上述指标〔不含(8)〕的相对危险度分别为(1)30.0,(2)1.4.(3)1.7,(4)0.7,(5)1.2,(6)2.2和(7)2.1;除(4)外所有指标均随年龄、接尘工龄和可吸入棉尘见识按尘量的增加而是增加趋势;与此同时,发现血清IgA,IgG和IgM含量高于对照组,而ANAE则低于对照组。
320 workers of two
factories processingpure cotton were studied. 1306 subjects with-out occupational dust
exposure were servedas controls. The median of inhalaboe dust,total dust and endotoxin were
found to be 0.71(0.41-1.51),5.28(3.04-12.32)mg/m3 and 2007(1236-4100)EU/m3 respectively.
The pre-valences of respiratory abnormalities in the cotton workers were(1)typical monday
sym-ptoms: 9.0%,(2)pst-shift FEV1 falling by5.0%or more:16.8%,(3)post-shift FEV1falling by
10%or more 4.2%,(4)FEV1 lessthan 80% predicted:6.1%,(5)FEV1/FVCless than
75%:4.0%,(6)cough and/or phl-egm:18.2%,(7)chronic bronchitis:10.9% and (8)byssinosis
defined by (1)plus(2) :1.7%.Comared with controls, the relative resks for the abovemedtioned
abnormatities except(8)were:(1)30.0,(2)1.4,(3)1.7,(4)1.7,(5)1.2,(6)2.2 and(7)2.1 respectively. With
the exceptionof (4),most of the prevalence increased withthe increase of age, duration of
exposure and cumulative inhalable dust exposure. Inaddition, the levels of IgA, IgA and IgM
ap-peared to be higher, and ANAE to be lowerin exposed group than those in the controls.
出处
《中国工业医学杂志》
CAS
1995年第6期329-333,共5页
Chinese Journal of Industrial Medicine
基金
加拿大IDRC提供资助
关键词
棉尘
棉尘病
职业病
cotton dust, endotoxin, lungfunction, byssinosis