母体丝虫感染对子代血嗜酸性粒细胞分类结果的影响

THE EFFECT OF MATERNAL FILARIAL INFECTION ONEOSINOPHIL IN PERIPHERAL BLOOD OF THEIR OFFSPRINGS

本文报告对安徽省人体班氏丝虫病流行区２２８对母子血样和７３例产妇血及其脐带血标本进行的白细胞分类计数和微丝蚴检查结果。结果显示，丝虫感染可使血中嗜酸性粒细胞的分类值明显上升。微丝蚴阳性母亲所生微丝蚴阴性子女其嗜酸性粒细胞分类值明显高于微丝蚴阴性母亲所生微丝蚴阴性子女的分类值（Ｐ＜０．０１）。检查出微丝蚴阳性母亲生育的子女其微丝蚴阳性率是微丝蚴阴性母亲生育的子女的２．８６倍。结果分析表明，宫内抗原的接触可致出生后的子女血中嗜酸性粒细胞升高，且此类子女对丝虫的易感性也增加。

This paper reported the results on differential count(DC) for blood samples of 228pairs of mothers with their children and 73 puperperas. It was clear that filarial infection had noeffect on blood neutrophils ,Lymphocytes and mono cytes count,but had an effect on eosinophilcount of these people. It was found that DC of eosinophils in microfilaria(Mf)+)mothers’ Mf(-)children under 10 years old were significantly higher than those in Mf(-)mothers’Mf(-)children( P<0. 01).On the other hand, a higher infection rate was observed in offsprings of in-fected mothers than in the offsprings of uninfected mothers(8%for childen in the former,2.8%for children in the latter. The results showed that the blood eosinophils in children who had peri-natal sensitization to filarial parasite antigens were elevated ,and these children were more suscep-tible to filarial infection.