摘要
复方蒿甲醚片是由抗疟新药苯芴醇与蒿甲醚配伍的新制剂，在抗药性恶性疟流行区治疗恶性疟现症病人５７例，临床治愈率１００％；平均退热时间３５．７±１８．２ｈ，原虫无性体转阴时间４０．１±１０．８ｈ，２８ｄ根治率９４．６％。用药后无不良反应，原虫配子体出现率２．１％。它对原虫在蚊体内孢子增殖有抑制效果。对减少疟疾传播有益，适宜于抗药性恶性疟的治疗。
Artemether Co.is a new preparation composed of two antimalarials,benflumetolumand
artemether. 57 clinical cases of drug一resistant falciparum malaria in endemic area were
treated.The result shows that the cure rate was 100%,mean fever clearance time35.7±
18.2h,asexial para-site clearance time 40.1±10.8h, radical cure rate during 28一day following
一up was 96.4%and ga-metocyte occurrance rate 2.1%. No side 一effect was
observed.Inhibitory effect on sporogony inmosquitos An.dirus also observed. This indicating
that the preparation is suitable for therapy of drug一resistant falciparum malaria and can
reduce malaria transmission.
出处
《中国寄生虫病防治杂志》
CSCD
1995年第4期244-246,共3页
Chinese Journal of Parasitic Disease Control
基金
WHO/TDR
昆明制药厂资助
关键词
疟疾
复方蒿甲醚片
治疗
Artemether, benflumetolum, drug一resistant falciparum
malaria, An. dirus
