413株细菌对氧氟沙星等3种喹诺酮类药物敏感试验

The sensitivity test of 413 strains to quinolones

用氧氟沙星、环丙沙星、诺氟沙星对从我院各种标本分享出的４１３株细菌作敏感试验，试验菌株有金葡球菌、克雷伯氏菌、大肠杆菌、绿脓假单胞菌等常见病原菌。药敏试验结果表明：这３种药物革兰氏阴性杆菌和部分革兰氏阳性球菌敏感率仍达７０％～９０％；甚至更高，但比以往文献报道的敏感率明显下降。本文提示要合理应用喹诺酮类药物，减少耐药菌株增加。

We isolated 413 strains of bacteria from the samples collected in ourhospital and made the test of their sensitivity to quinolone. Results showed the commonbacteria are S.aureus. K. pneumoniae. E. coli and P. aeruginosa. and P. aeruginosa is themost prevalent(111 strains. 26. 8%).The sensitivity test shows the quiriolone is aneffective drug against Gram- positive cocci and Gram-negative bacilli. The sensitivityrate isaround 70%～90%。 It is lower than the previous reports. So we suggest to rationalize theusage of the quinolones to reduce the bacteial resistance.