摘要
在综述国内外研究成果的基础上,回顾胶原蛋白以及与合成高分子形成的复合材料(主要是水凝胶)在生物医学领域方面的研究现状,对该材料今后的发展方向也做了初步的探讨。胶原蛋白和一些合成高分子化合物(如聚甲基丙烯酸羟乙酯,聚乙烯醇等),作为生物材料已得到广泛的应用,而两者形成的复合材料水凝胶具有良好的生物相容性和理化性质,是一类新型的生物材料,具有很大的研究和应用价值。该材料可用于软组织替代物、药物释放系统、组织引导再生、组织工程等方面,成为一类“理想”的生物材料。
In this article, we review some major progresses made in the field of biomedical materials research on the application of collagen protein and its composites formed with certain synthetic polymers (e. g. polyhydroxyethyl methacrylate and polyvinyl alcohol). Some potential development and application of the materials are discussed tentatively. Due to their biocompatibility and physico-chemical properties, the collagen-synthetic polymer hydrogels will find wide application in soft tissue substitution, drug delivery system, guided tissue regeneration, tissue engineering, etc.
出处
《中国科学基金》
CSCD
1995年第4期14-18,共5页
Bulletin of National Natural Science Foundation of China
