活血素治疗脑血管疾病的实验参数变化

Change in laboratory parameters after vasobral treatment of cerebrovascular disease

用活血素（二氢麦角隐亭）治疗２１例脑血管疾病患者，治疗前后用毛细管法及椎板法观察血液流变学、红细胞变形性、血小板聚集、红细胞刚性指数、体外血栓、血脂及三种认知功能；ＭＭＳＥ、ＨＤＳ、ＳＰＭＳＱ。治疗后发现血流变、体外血栓、红细胞刚性均好转，三种认知功能均有提高；另用大白鼠口服活血素３个月，病理及电镜观察脏器变化，发现其肝、肾、肾上腺、脑、视网膜微血管明显扩张，微血管内红细胞充盈良好，这对临床症状改善提供了一些理论依据。

Patients with cerebrovascular diseases were detemined hemorheology in both using capillary viscometer and rotary cone-plate viscometer, platelet aggregation, erythrocyte rigidity index, extracorporeal. serum lipid and three congnition function(MMSE, HDS, SPMSQ) before and after vasobral treatment for three months. In the assessment of the results were considered to improve hemorheology,extracorporeal and cognition function. The experiment of rats after vasobral fed. Hyperemia and dilation of the capillaey in liver,kindey,adrenal,brain and retina,these data suggest that some theories related to improve the symptoms of patients.