老年单纯舒张型高血压患者血液流变学和左心参数改变

Changes of left ventricular parameters and hemorheological indices in senile patients with Isolated Diostolic Hypertension

对３５例老年单纯舒张型高血压患者血液流变学和左心参数测定的结果表明：老年单纯舒张型高血压患者血液粘度高于正常人，左心结构和舒张功能随病程的延长而出现异常。推测血液粘度增高，特别是高切变率血粘度增高和纤维蛋白原增加可能参与老年单纯舒张型高血压患者舒张压的形成，老年单纯舒张压升高也是心脏靶器官损害的危险因素。

Hemorheological indices and left ventricular parameters were determined in 35 senile patients with Isolated Diastolic Hypertension(IDH). The results demonstrated that: (1) The whole blood viscosity was higher in senile patients with IDH than that of the normal control group; (2)the changes of the left-heart structure and diastolic function were correlated with the severity and duration of IDH. It is suggested that the increased high shear rate and the high fibrinogen might be responsible for the high diastolic pressure in the patients of IDH.