摘要
656例MB型麻风用WHO—MDT24个月,停药后监测1～8年。临床显著进步629例(95.88％),进步23例(3.51％),有效率为99.39％。监测5年累计细菌阴转535例,在初治者402例小为99.46％,经治者254例中为99.18％;治疗前BI<3.0的299例中监测5年累计阴转率为100％,BI≥3.0的357例中为99.3％。治疗及监测期间,其发生麻风反应140例(21.34％),其小Ⅰ型47例,Ⅱ型61例,神经炎32例。1例在监测5年时复发。作者认为应适当延长MDT监测时间进一步了解复发情况,以便对MDT的疗效作出确切评价。
For one to eight years 656 persons who had had MB leprosy and completed WHO - MDT have followed up. Significant improvement rate was 99. 39%. When monitoring time reached five years,BI changed to negative in 535 persons(81. 6%) ,particularly in those who had BI below 3. 0 before MDT. In the period of treatment and monitoring lepra reaction occur-rred in 140 persons(21. 34%), including type I in 47,type II in 61 and neuritis in 32. One person's leprosy has relapsed in the fifth year of monitoring, so the authors suggest that the mon-
基金
WHO资助
