情感性障碍高发家系的遗传学调查

Genetics investigation on high density family of affective disorder.

本文调查３０例情感性障碍高发家系的一、二、三级亲属成员共１０９６人，患各类精神疾病１０５例，患病率为９．５８％，其中情感性障碍６４例，占６０．９５％．调查资料表明，各级亲属患病率是亲缘关系越近，患病率越高，远超于群体患病率。本文还就遗传方式进行了探讨，提出情感性障碍以伴性遗传的可能性大．

Thirty high density families of affective disorder were investigated. The total number of first, second and third degree relatives was 1096, in which 105 people had various mental disorders and the prevalence rate was 9.58%.There were 64 (60.95%) affective disorder patients in all the patients investigated. The results suggested that the closer the relationship with affective disorder patients was,the higher the prevalence rate was. Authors consider that affective disorder may be inherited by sex linked inheritance.