MEBO在烧伤临床中的应用与疗效评价(附217例报告)

Clinical Application of MEBO for Treating Thermal Injuries

本文报告了我院1990年至1995年，应用MEBT治疗217例烧伤，其中最大面积60％，深Ⅱ度50例占23．04％、Ⅲ度19例占8．76％；烧伤95例占43．77％，烫伤83例占38．24％。采用MEBO与京万红进行了比较试验，结果两种药物在浅Ⅱ度烧伤创面无明显统计学差异，在深Ⅱ度至Ⅲ度创面MEBO显示了明显优势，P＜0．05，对愈后瘢疤形成率进行了统计学标准化率的计算，结果显示，MEBO标准化率为3．7％，京万红标准化率为9．22％，显著性检验结果显示，P＜0．01差别有非常显著意义，即京万红愈后瘢痕形成率明显高于MEBO，提出了6条治疗方法，217例烧伤病例中除一例子伤后10天合并多脏器衰竭上消化造大出血死亡外，余216例全部治愈，通过217例烧伤病人的治疗及意后半年以上复查，证实了MEBO深Ⅱ度创面治疗后，可不留瘢痕的科学正确结论，笔者认为MEBT和MEBO是临床值得推广普及的理想方法和药物。

This paper reports the results of applying MEBOfor treating 217 cases of thermal injury. The largestinjured area was 60%BSA. Among them, 50 caseshad deep second degree wound accounted for23. 04%. 19 cases had third degree wound accountedfor 8. 76%. 95 cases were burned accounted for 43.77% and 83 cases were scalded accounted for 38.24%. The patients were treated with MEBO or Jing-wanhong ointment. A comparison between the effica-cy of the two drugs was made. For superficial seconddegree burn, MEBO showed slight superiority overJingwanhong ointment. (P>0.05). For deep secondand third degree burns MEBO showed significant supe-riority over Jingwanhong ointment (P <0. 05 ). A cal-culation of the statistically standardized rate of theformation of scar post healing showed that MEBO hada standarized rate of scar formation of 3. 7%, whileJingwanhong ointment had a standardized rate of scarformation of 9. 22%. The difference betweery the twogroups was very significant (P<0.01). Jingwanhongointment group had a much higher scar formation ratethan MEBO group.The authors suggested some points for attentionin the course of treatment. One patient died from mul-tiple system organ failure and massive hemorrhage ofupper digestive tract. 216 patients all cured. After fol-lowed up for more than 6 months, MEBO proved toleave no scar after healing for deep second degreeburns.