新型隐球菌性脑膜炎预后的影响因素

Influential factors on the prognosis of cryptococcal meningtis

对４０例预后各异的新型隐球菌性脑膜炎２０项流行病学，临床表现及实验室检查参数的比较分析，发现来自农村地区，外周血象白细胞总数升高而淋巴细胞分类降低，视乳头水肿，脑脊液压力过高，应用抗生素和激素超过１０天，二性霉素Ｂ治疗量达不到２０００ｍｇ及未与５—Ｆｃ配伍者，预后不良。

A retrospective analysis of 20 indexes of the epidemiology,clinical manifestations and laboratory investigations was done in 40 patients with different prognostic cryptococcal meningitis. Some factors in cryptococcal meningitis such as patients from the rural areas,high total white cell count with low percentage of lymphocytes,papilloedema,over raised CSF pressure,the use of antibiotics and steroids more than 10 days,amphotericin B less than 2000mg and no administration of 5-Flurocytosine appered to be associated with a worse prognosis.