高效价巨细胞病毒免疫球蛋白的制备及初步应用

Preparation and Preliminarily Application of High Titer Cytomegalovirus IgG

应用ELISA法筛选巨细胞病毒（CMV）IgG效价≥1：30000的人血浆，合并后，按低温乙醇法精制出高效价CMV－IgG。经小规模人体应用观察无不良反应，且有71．4％（50／70）的CMV－IgM或CMV-IgA阳性人的血清转阴。

The human plasma containing high titer (≥1: 30000) cytomegalovirus(CMV)IgG was screened by ELISA and used for preparing high titer CMV-IgG by coldethanol fractionation method. Small-scale clinical trial revealed that average the patientstreated with CMV-IgG whose CMV-IgM or CMV-IgA were pos1tive with a serum averageconversion rate of 71．4％(50/70),and no adverse reaction was found.