摘要
48例糖尿病患者血浆心钠素高于正常人(875.2±50vs 542.5±23.8ng/L)。血浆ANF与同期胰岛素、左房内径呈正相关;与植物神经功能积分有一定相关但无统计学意义;与病程、24小时尿钠、血糖、糖化血红蛋白、右房横径无相关性。9例糖尿病性心脏病患者和6例糖尿病性肾病患者血浆ANF高于无明显临床合并症者。OGTT中,ANF在服糖1、2、3小时均明显低于空腹水平。
The mean plasma ANF level in 48 patients with diabetes mellitus was higher than that in normal subjects (875.2 ± 50.0vs542.5 ± 23.8ng/L). And ANF levels were positively correlated with serum insulin and the dimension ofleft atria. There was some relationship between ANF and cardiac autonomic function score, but it's not statistically significant. No significant correlation was observed between plasma ANF and the duration of diabetes, urine sodium, blood glucose or HbA1C levels. The levels of plasma ANF in 9 patients with cardiac complication and 6 patients with diabetic nephro-pathy were both higher than that in patients without any obvious complication. The decrease of plasma ANF in OGTT was due to a fall of extracellular volume, and had little relation with the changes of serum insulin.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1989年第3期143-145,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
心钠素
糖尿病
胰岛素
Atrial natriuretic factor Diabetes mellitus Insulin
