摘要
本文测定了50例NIDDM患者和26例正常健康人红细胞钠含量和钠转运。结果表明:糖尿病患者红细胞钠含量明显高于正常人,红细胞钠泵活性明显低于正常人,而糖尿病患者红细胞膜对钠的通透性与正常人差异则无显著性。女性糖尿病患者红细胞钠含量和钠泵活性的变化比男性患者为大。胰岛素在体外能明显降低糖尿病患者红细胞钠含量和升高红细胞钠泵活性。
The erythrocyte sodium content and sodium transport in 50 cases of diabetic patients (NIDDM) and 26 cases of normal subjects were determined. The results showed that the sodium content of erythrocyte was obviously higher in the diabetic patients than that in the normal subjects, the activity of Na-pumps of erythrocyte was obviously lower in diabetic patients than that in normal subjects, but there was no significant difference of permeability of erythrocyte membrane to sodium observed. The changes of erythrocyte sodium content and the activity of Na-pumps of erythrocyte were obviously greater in female diabetic patients than those in male diabetic patients. The addition of insulin in vitro at a concentration of 5mg/L significantly decreased the erythrocyte sodium content and increased the activity of Na-pumps of erythrocyte in diabetic patients.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1989年第3期152-154,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
糖尿病
红细胞钠含量
膜通透性
Diabetes mellitus Erythrocyte Sodium content Membrane permeability Activity of the sodium pumps