摘要
用放免法测定31例急性颅脑损伤患者脑脊液(CSF)中生长抑素(SS)的含量。结果:脑外伤后48hCSF中SS含量明显低于对照组(P<0.01),伤后6~10天SS浓度升高,与对照组相比无明显差异。GCS≤8分者CSF中SS含量显著低于GCS>8分者(P<0.05);上消化道出血组SS低于非出血组(P<0.005)。提示:SS可能参与了急性颅脑损伤的发病过程。SS水平降低可能与间接诱发急性上消化道疾病之间存在着某种联系。
The levels of somatostatin(SS)were
determined byradioimmunoassay in the cerebrodpinal fluid(CSF ) of 31patients with acute brain
injury.48 hrs after brain in-iury,the levels of SS in the CSF were significantly lowerthan the
control group(P<0.01).6一10 days after braininjury,the levels of SS rose and there was no
differencecompared with the control group.The levels of SS in GCS≤8 group were significantly
lower than GCS>8group(p<0.05).Thje levels of SS in patients woth hem- orrhage of upper
digestive tract were lower than the pa-tients without the disease(P<0.05).It is suggested thatSS
may be invulved in the mechanism of acute brain in-jury and the decrease of SS levels may be
related to the-indirect induction of the disease of upper digestive tract.
出处
《中国危重病急救医学》
CAS
CSCD
1995年第3期154-155,共2页
Chinese Critical Care Medicine
关键词
颅脑损伤
脑脊液
生长抑素
brain
injury
cerebrospinal fluid
somato- statin